{"id":17843,"date":"2015-04-05T00:23:14","date_gmt":"2015-04-04T21:23:14","guid":{"rendered":"http:\/\/balarisi.org\/?p=17843"},"modified":"2015-04-09T12:13:56","modified_gmt":"2015-04-09T09:13:56","slug":"ege-bolgesinde-tuketime-sunulan-ballarda-sulfonamid-kalintilarinin-arastirilmasi","status":"publish","type":"post","link":"https:\/\/www.beyazkovan.com\/?p=17843","title":{"rendered":"Ege b\u00f6lgesinde t\u00fcketime sunulan ballarda s\u00fclfonamid kal\u0131nt\u0131lar\u0131n\u0131n ara\u015ft\u0131r\u0131lmas\u0131"},"content":{"rendered":"<p><strong>Ramazan Uluda\u011f<\/strong><br \/>\nY\u00fcksek Lisans Tezi, Adnan Menderes \u00dcniversitesi \/ Sa\u011fl\u0131k Bilimleri Enstit\u00fcs\u00fc \/ Farmakoloji ve Toksikoloji Anabilim Dal\u0131, 2008, 76 s.<br \/>\nTEZ NO: <strong>195628<\/strong><br \/>\n<!--more--><span style=\"color: #ff6600;\"><a style=\"color: #ff6600;\" href=\"https:\/\/tez.yok.gov.tr\/UlusalTezMerkezi\/tarama.jsp\" target=\"_blank\">Sorgu Penceresine TEZ NO&#8217;yu yazarak Ayr\u0131nt\u0131l\u0131 Bilgi ve PDF d\u00f6k\u00fcmana ula\u015fmak i\u00e7in t\u0131klay\u0131n\u0131z <\/a><\/span><\/p>\n<p><strong>\u00d6ZET<br \/>\n<\/strong> Avrupa Birli\u011fi d\u00fczenlemelerine g\u00f6re antimikrobiyel ajanlar i\u00e7in `azami kal\u0131nt\u0131 seviyesi (AKS)\u2019 belirlenmemi\u015f olup, bal \u00fcretimi yap\u0131l\u0131rken antibiyotik kullan\u0131lmas\u0131na m\u00fcsaade edilmemektedir. \u00dclkemizde s\u00fclfonamid grubu antibiyotikler bal \u00fcreticileri taraf\u0131ndan illegal olarak yayg\u0131n bir \u015fekilde kullan\u0131lmaktad\u0131r. Bu \u00e7al\u0131\u015fman\u0131n amac\u0131, Ege B\u00f6lgesi\u2019nde t\u00fcketime sunulan ballar\u0131n s\u00fclfonamid grubu antibiyotik kal\u0131nt\u0131lar\u0131 y\u00fcn\u00fcnden ara\u015ft\u0131r\u0131lmas\u0131d\u0131r. Bu ama\u00e7la, \u00fcretim miktarlar\u0131 g\u00f6z \u00f6n\u00fcnde tutularak b\u00f6lge illerinden toplam 103 adet bal \u00f6rne\u011fi toplanm\u0131\u015ft\u0131r. Bu \u00f6rnekler, metot geli\u015ftirme ve validasyonu takiben s\u0131v\u0131-s\u0131v\u0131 faz y\u00f6ntemi ile \u00f6z\u00fctleme sonras\u0131 Y\u00fcksek Bas\u0131n\u00e7l\u0131 S\u0131v\u0131 Kromotografi (HPLC) cihaz\u0131nda, florasan detekt\u00f6r arac\u0131l\u0131\u011f\u0131nda, kolon sonras\u0131 t\u00fcrevlendirme metodu ile 7 s\u00fclfonamid t\u00fcrevi (s\u00fclfanilamid, s\u00fclfadiazin, s\u00fclfatiyazol, s\u00fclfamerazin, s\u00fclfametazin, s\u00fclfametoksazol ve s\u00fclfadimetoksin) y\u00f6n\u00fcnden analiz edilmi\u015flerdir.Y\u00f6ntemde, s\u00fclfanilamid, s\u00fclfadiazin, s\u00fclfatiyazol, s\u00fclfamerazin, s\u00fclfametazin, s\u00fclfametoksazol s\u00fclfadimetoksinin s\u0131ras\u0131yla; ortalama % geri al\u0131mlar\u0131; 62,37, 64,10, 62,57, 67,11, 66,94, 57,31, 53,99, % standart sapmalar\u0131 (RSD); 8,01, 7,02, 6,83, 6,57, 7,57, 7,06, 7,88, de\u011ferlendirme seviyeleri; 6,83, 5,36, 5,51, 6,67, 7,34, 5,02, 6,73 ng\/g olarak hesaplanm\u0131\u015ft\u0131r. Ege b\u00f6lgesinden toplanan 103 bal\u0131n % 23\u2019\u00fcnde s\u00fclfonamid kal\u0131nt\u0131s\u0131 tespit edilmi\u015f olup, pozitif \u00f6rneklerin % 68\u2019inin s\u00fclfametazin, % 12\u2019sinin s\u00fclfamerazin, ve % 20\u2019sinin de s\u00fclfametoksazol ile kontamine oldu\u011fu belirlenmi\u015ftir.Sonu\u00e7 olarak, toplanan bal \u00f6rneklerinde yayg\u0131n olarak s\u00fclfonamid kal\u0131nt\u0131lar\u0131na rastlanm\u0131\u015f olup Ege B\u00f6lgesi ar\u0131 yeti\u015ftiricilerinin yasad\u0131\u015f\u0131 olarak bu ila\u00e7lar\u0131 kulland\u0131klar\u0131 anla\u015f\u0131lmaktad\u0131r. Bu sorunu \u00f6nlemek i\u00e7in yeti\u015ftiricilerin e\u011fitilmesi, denetimlerin art\u0131r\u0131lmas\u0131 ve cayd\u0131r\u0131c\u0131 cezai i\u015flemlerin y\u00fcr\u00fcrl\u00fc\u011fe sokulmas\u0131 fayda sa\u011flayabilece\u011fi gibi toplum sa\u011fl\u0131\u011f\u0131 korunacak ve \u00fclke ekonomisine de katk\u0131da bulunulacakt\u0131r.<br \/>\n<strong>Anahtar Kelimeler: <\/strong> HPLC-FLD; bal; kal\u0131nt\u0131; s\u00fclfonamid<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ramazan Uluda\u011f Y\u00fcksek Lisans Tezi, Adnan Menderes \u00dcniversitesi \/ Sa\u011fl\u0131k Bilimleri Enstit\u00fcs\u00fc \/ Farmakoloji ve Toksikoloji Anabilim Dal\u0131, 2008, 76 s. TEZ NO: 195628<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"footnotes":""},"categories":[37],"tags":[],"class_list":["post-17843","post","type-post","status-publish","format-standard","","category-yuksek-lisans-tezleri","yazarlar-ramazan-uludag","anahtarkelimeler-antibiyotik-kalintisi","anahtarkelimeler-bal","anahtarkelimeler-bal-analizi","anahtarkelimeler-bal-ve-kalinti-sorunu","anahtarkelimeler-bal-ve-yoresel-arastirmalar","anahtarkelimeler-ege-bolgesi","anahtarkelimeler-kalinti","anahtarkelimeler-kalinti-analizi","anahtarkelimeler-sulfonamid","anahtarkelimeler-yoresel-arastirmalar"],"_links":{"self":[{"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=\/wp\/v2\/posts\/17843","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=17843"}],"version-history":[{"count":1,"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=\/wp\/v2\/posts\/17843\/revisions"}],"predecessor-version":[{"id":17844,"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=\/wp\/v2\/posts\/17843\/revisions\/17844"}],"wp:attachment":[{"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=17843"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=17843"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=17843"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}