{"id":17815,"date":"2015-04-03T12:17:54","date_gmt":"2015-04-03T09:17:54","guid":{"rendered":"http:\/\/balarisi.org\/?p=17815"},"modified":"2015-04-09T12:22:35","modified_gmt":"2015-04-09T09:22:35","slug":"in-vitro-kosullarda-propolisin-antibakteriyel-antifungal-ve-leyismanyasidal-etkilerinin-arastirilmasi","status":"publish","type":"post","link":"https:\/\/www.beyazkovan.com\/?p=17815","title":{"rendered":"In vitro ko\u015fullarda propolis\u2019in antibakteriyel, antifungal ve leyi\u015fmanyasidal etkilerinin ara\u015ft\u0131r\u0131lmas\u0131"},"content":{"rendered":"<p><strong>G\u00fclay G\u00fclbol Duran<\/strong><br \/>\nY\u00fcksek Lisans Tezi, Mustafa Kemal \u00dcniversitesi \/ Fen Bilimleri Enstit\u00fcs\u00fc, 2007, 63 s.<br \/>\nTEZ NO: <strong>79938<\/strong><br \/>\n<!--more--><span style=\"color: #ff6600;\"><a style=\"color: #ff6600;\" href=\"https:\/\/tez.yok.gov.tr\/UlusalTezMerkezi\/tarama.jsp\" target=\"_blank\">Sorgu Penceresine TEZ NO&#8217;yu yazarak Ayr\u0131nt\u0131l\u0131 Bilgi ve PDF d\u00f6k\u00fcmana ula\u015fmak i\u00e7in t\u0131klay\u0131n\u0131z <\/a><\/span><\/p>\n<p><strong>\u00d6ZET<br \/>\n<\/strong>Propolis, yap\u0131s\u0131nda 300\u2019den fazla biyolojik olarak aktif bileseni olan ve kompozisyonuile bilesenlerinin oranlar\u0131 b\u00f6lgeden b\u00f6lgeye ve bitki t\u00fcrlerine bagl\u0131 olarak degiskenlik g\u00f6sterenbir ar\u0131 \u00fcr\u00fcn\u00fcd\u00fcr. Adana orijinli propolisin baz\u0131 Gram pozitif (Staphylococcus aureus ATCC25923, Staphylococcus aureus ATCC 29213, Staphylococcus epidermidis ATCC 12228,Enterococcus faecalis ATTCC 29212) standart suslar\u0131 ile Gram pozitif klinik izolat\u0131(Streptococcus pyogenes) ve Gram negatif (Esherichia coli ATCC 25922, Pseudomonasaeruginosa ATCC 27853, Enterobacter cloacae ATCC 13047) standart suslar\u0131 ile Gramnegatif klinik izolatlar\u0131na (Proteus vulgaris, Enterobacter aerogenes) kars\u0131 antibakteriyel,maya formundaki mantarlardan ise Candida albicans ATCC 90028, Candida krusei ATCC6258, Candida glabrata ATCC 32554, Candida tropicalis ATCC 22019 standart suslar\u0131 veklinik bir izolat olan Candida parapsilosis\u2019e kars\u0131 antifungal aktivitelerinin varl\u0131g\u0131, ayr\u0131caLeishmania tropica\u2019n\u0131n 5 farkl\u0131 klinik izolat\u0131na kars\u0131 Leyismanyasidal aktivitesinin varl\u0131g\u0131arast\u0131r\u0131lm\u0131st\u0131r. Antimikrobiyal aktivite \u00e7al\u0131smalar\u0131 makrodil\u00fcsyon y\u00f6ntemi kullan\u0131larak CLSI\u00f6nerileri dogrultusunda yap\u0131lm\u0131st\u0131r. Propolis \u00f6rneklerinin Gram pozitif bakterilere kars\u0131antibakteriyel etkileri ( MIK degeri 64-1024 ?g\/ml), Gram negatif ( MIK degeri 256-1024?g\/ml) ve maya suslar\u0131na kars\u0131 olan antimikrobiyal aktivitelerinden ( MIK degeri 128-1024?g\/ml) daha y\u00fcksek olarak bulunmustur. Mayalara kars\u0131 etkinligin Gram negatif bakterilerenazaran daha y\u00fcksek oldugu saptanm\u0131st\u0131r. Leishmania tropica izolatlar\u0131nda isekonsantrasyonun 250 ?g\/ml, 500 ?g\/ml ve 750 ?g\/ml d\u00fczeyine \u00e7\u0131kar\u0131lmas\u0131 durumundapropolisin leyismanyasidal etkisinin varl\u0131g\u0131 a\u00e7\u0131k\u00e7a saptanm\u0131st\u0131r. Gerek h\u00fccre say\u0131s\u0131ndaistatistiksel olarak anlaml\u0131 derecede azalman\u0131n tespit edilmesi gerekse h\u00fccre yuvarlaklasmas\u0131,kuyruk kayb\u0131, n\u00fckleer yap\u0131n\u0131n b\u00fcy\u00fcmesi ve sitoplazmik yap\u0131n\u0131n daralmas\u0131 gibi morfolojikdegisimlerin oldugu tespit edilmistir.<br \/>\n<strong>Anahtar Kelimeler: <\/strong> Propolis; Propolisin Kimyasal \u00d6zellikleri; antibakteriyal aktivite; antifungal aktivite; leyi\u015fmanyasidal aktivite<\/p>\n","protected":false},"excerpt":{"rendered":"<p>G\u00fclay G\u00fclbol Duran Y\u00fcksek Lisans Tezi, Mustafa Kemal \u00dcniversitesi \/ Fen Bilimleri Enstit\u00fcs\u00fc, 2007, 63 s. TEZ NO: 79938<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"footnotes":""},"categories":[37],"tags":[],"class_list":["post-17815","post","type-post","status-publish","format-standard","","category-yuksek-lisans-tezleri","yazarlar-gulay-gulbol-duran","anahtarkelimeler-antifungal-etki","anahtarkelimeler-antimikrobiyal-etki","anahtarkelimeler-leyismanyasidal-etki","anahtarkelimeler-propolis"],"_links":{"self":[{"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=\/wp\/v2\/posts\/17815","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=17815"}],"version-history":[{"count":1,"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=\/wp\/v2\/posts\/17815\/revisions"}],"predecessor-version":[{"id":17816,"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=\/wp\/v2\/posts\/17815\/revisions\/17816"}],"wp:attachment":[{"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=17815"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=17815"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=17815"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}