{"id":17809,"date":"2015-04-03T12:07:53","date_gmt":"2015-04-03T09:07:53","guid":{"rendered":"http:\/\/balarisi.org\/?p=17809"},"modified":"2015-04-09T14:47:48","modified_gmt":"2015-04-09T11:47:48","slug":"sodyum-tetraboratin-buyuk-bal-mumu-guvesi-galleria-mellonella-l-lepidopterapyralidaenin-yasama-gelisimi-ve-bazi-enzimlerinin-aktivitesi-uzerine-etkisi","status":"publish","type":"post","link":"https:\/\/www.beyazkovan.com\/?p=17809","title":{"rendered":"Sodyum tetraborat\u0131n b\u00fcy\u00fck bal mumu g\u00fcvesi Galleria mellonella L.(Lepidoptera:Pyral\u0131dae)\u2019n\u0131n ya\u015fama, geli\u015fimi ve baz\u0131 enzimlerinin aktivitesi \u00fczerine etkisi"},"content":{"rendered":"<p><strong>Yonca Durmu\u015f<\/strong><br \/>\nY\u00fcksek Lisans Tezi, Zonguldak Karaelmas \u00dcniversitesi \/ Fen Bilimleri Enstit\u00fcs\u00fc \/ Biyoloji Anabilim Dal\u0131, 2007, 75 s.<br \/>\nTEZ NO: <strong>199795<\/strong><br \/>\n<!--more--><span style=\"color: #ff6600;\"><a style=\"color: #ff6600;\" href=\"https:\/\/tez.yok.gov.tr\/UlusalTezMerkezi\/tarama.jsp\" target=\"_blank\">Sorgu Penceresine TEZ NO&#8217;yu yazarak Ayr\u0131nt\u0131l\u0131 Bilgi ve PDF d\u00f6k\u00fcmana ula\u015fmak i\u00e7in t\u0131klay\u0131n\u0131z <\/a><\/span><\/p>\n<p><strong>\u00d6ZET<br \/>\n<\/strong> B\u00fcy\u00fck bal mumu g\u00fcvesi Galleria mellonella L. yapay besin ortam\u0131nda beslenerek sodyumtetraborat\u0131n b\u00f6ce\u011fin ya\u015fama, geli\u015fimi, ergin \u00f6m\u00fcr uzunlu\u011fu ile 7. evre larvalar\u0131n\u0131nhemolenf ve ya\u011f dokusunda malondialdehid (MDA) ve lizozim miktar\u0131, glutatyon S-transferaz (GST), alanin aminotransferaz (ALT), aspartat aminotransferaz (AST) ve asetilkolinesteraz (AChE) enzimlerinin aktivitesi \u00fczerine etkisi incelendi. Sodyum tetraborat\u0131n0,3 g\u2019\u0131 7. evreye ula\u015fan larva oran\u0131n\u0131 % 17,5 \u00c2\u00b1 2,9\u2019a istatistiksel olarak \u00f6nemli dereceded\u00fc\u015f\u00fcrm\u00fc\u015f, 7. evreye ula\u015fma s\u00fcresini ise ortalama 5 g\u00fcn geciktirmi\u015ftir. Bu miktar\u0131 i\u00e7erenbesinden % 12,5 oran\u0131nda pup ve ergin elde edilmi\u015f ve bu evrelere ula\u015fmak i\u00e7in gereklis\u00fcre ise ortalama 5 g\u00fcn uzam\u0131\u015ft\u0131r. Kontrol besini ile yeti\u015ftirilen erginlerin \u00f6m\u00fcr uzunlu\u011fuortalama 9,0 \u00c2\u00b1 0,7 g\u00fcn iken sodyum tetraborat\u0131n 0,2 g\u2019\u0131n\u0131 i\u00e7eren besin ile yeti\u015ftirilenerginler kontrole g\u00f6re 4,2 g\u00fcn daha uzun (13,2 \u00c2\u00b1 1,9 g\u00fcn) ya\u015fam\u0131\u015ft\u0131r. Denenen en y\u00fcksekiii\u00d6ZET (devam ediyor)madde miktar\u0131 erginlerin \u00f6m\u00fcr uzunlu\u011funu \u00f6nemli derecede k\u0131saltm\u0131\u015ft\u0131r. Sodyumtetraborat\u0131n y\u00fcksek konsantrasyonlar\u0131 larvalar\u0131n hemolenf ve ya\u011f doku MDA miktar\u0131n\u0131\u00f6nemli derecede art\u0131rm\u0131\u015ft\u0131r. Sodyum tetraborat\u0131n y\u00fcksek konsantrasyonlar\u0131 (0,2 ve 0,3 g)hemolenf GST aktivitesinde istatiksel olarak \u00f6nemli bir azalmaya sebep olurken, sodyumtetraborat\u0131n t\u00fcm konsantrasyonlar\u0131 ya\u011f doku GST aktivitesini art\u0131rm\u0131\u015ft\u0131r. En y\u00fckseksodyum tetraborat konsantrasyonu (0,3 g) ya\u011f doku GST aktivitesini yakla\u015f\u0131k 12 katart\u0131rm\u0131\u015ft\u0131r. Besindeki sodyum tetraborat\u0131n y\u00fcksek konsantrasyonlar\u0131, hemolenf ve ya\u011fdoku lizozim enzimi miktar\u0131n\u0131 \u00f6nemli derecede d\u00fc\u015f\u00fcrm\u00fc\u015ft\u00fcr. Sodyum tetraborat\u0131n d\u00fc\u015f\u00fckkonsantrasyonlar\u0131 ya\u011f doku lizozim miktar\u0131n\u0131 \u00f6nemli derecede art\u0131rm\u0131\u015ft\u0131r. Bu y\u00fcksekkonsantrasyonlar hemolenf ALT, AST ve AChE aktivitesini \u00f6nemli derecede azalt\u0131rken,ya\u011f doku ALT, AST ve AChE aktivitesini \u00f6nemli derecede art\u0131rm\u0131\u015ft\u0131r. Bu \u00e7al\u0131\u015fma sodyumtetraborat taraf\u0131ndan olu\u015fturulan oksidatif stresin b\u00fcy\u00fck bal mumu g\u00fcvesinde baz\u0131metabolik i\u015flevleri ve sinaptik iletimi olumsuz y\u00f6nde etkiledi\u011fini, oksidatif strese kar\u015f\u0131b\u00f6ce\u011fin \u00e7e\u015fitli biyokimyasal ve fizyolojik adaptasyon tepkileri verdi\u011fini g\u00f6stermi\u015ftir. Eldeedilen sonu\u00e7lar sodyum tetraborat\u0131n b\u00f6ce\u011fin ya\u015fama, geli\u015fme ve \u00f6m\u00fcr uzunlu\u011fu\u00fczerindeki olumsuz etkisinde oksidatif stresin \u00f6nemli bir fakt\u00f6r olabilece\u011finidesteklemektedir.<br \/>\n<strong>Anahtar Kelimeler: <\/strong>Galleria mellonella, sodyum tetraborat, ya\u015fama, \u00f6m\u00fcr uzunlu\u011fu,glutatyon S-transferaz, transaminazlar, asetilkolinesteraz<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Yonca Durmu\u015f Y\u00fcksek Lisans Tezi, Zonguldak Karaelmas \u00dcniversitesi \/ Fen Bilimleri Enstit\u00fcs\u00fc \/ Biyoloji Anabilim Dal\u0131, 2007, 75 s. TEZ NO: 199795<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"footnotes":""},"categories":[37],"tags":[],"class_list":["post-17809","post","type-post","status-publish","format-standard","","category-yuksek-lisans-tezleri","yazarlar-yonca-durmus","anahtarkelimeler-mum-guvesi"],"_links":{"self":[{"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=\/wp\/v2\/posts\/17809","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=17809"}],"version-history":[{"count":1,"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=\/wp\/v2\/posts\/17809\/revisions"}],"predecessor-version":[{"id":17810,"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=\/wp\/v2\/posts\/17809\/revisions\/17810"}],"wp:attachment":[{"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=17809"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=17809"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=17809"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}