{"id":17199,"date":"2014-07-07T00:31:25","date_gmt":"2014-07-06T21:31:25","guid":{"rendered":"http:\/\/balarisi.org\/?p=17199"},"modified":"2015-03-31T15:30:49","modified_gmt":"2015-03-31T12:30:49","slug":"balarilarinda-apis-mellifera-l-fosfoglukomutaz-pgm-enzim-polimorfizminin-mevsimlere-bagli-olarak-degisiminin-nedenlerinin-ve-sonuclarinin-arastirilmasi","status":"publish","type":"post","link":"https:\/\/www.beyazkovan.com\/?p=17199","title":{"rendered":"Balar\u0131lar\u0131nda (Apis mellifera L.) Fosfoglukomutaz (Pgm) enzim polimorfizminin mevsimlere ba\u011fl\u0131 olarak de\u011fi\u015fiminin nedenlerinin ve sonu\u00e7lar\u0131n\u0131n ara\u015ft\u0131r\u0131lmas\u0131"},"content":{"rendered":"

KENCE, Meral<\/a>; BANERJEE, Sreeparma
\n<\/a><\/strong>T\u00dcB\u0130TAK TBAG Proje 106T181, 2008: 1-54
\nMakale No:\u00a097989<\/strong>
\nSorgu Penceresine MAKALE NO\u2019yu yazarak Ayr\u0131nt\u0131l\u0131 Bilgi ve PDF d\u00f6k\u00fcmana ula\u015fmak i\u00e7in t\u0131klay\u0131n\u0131z<\/a><\/span><\/p>\n

\u00d6ZET<\/strong>
\nFosfoglukomutaz enzimi (PGM), glikojen metabolizmas\u0131, pentoz fosfat yolu ve ana glikolitik koridor aras\u0131ndaki kav\u015fak noktas\u0131nda bulunan, enerji metabolizmas\u0131ndaki \u00f6nemli enzimlerden biri olup s\u00f6z\u00fc ge\u00e7en metabolik yolda, glukoz-1-fosfat ve glukoz-6-fosfat aras\u0131ndaki iki y\u00f6nl\u00fc d\u00f6n\u00fc\u015f\u00fcm\u00fc katalizlemektedir. Hatay, Artvin ve K\u0131rklareli illerinden y\u0131l boyunca her ay al\u0131nan toplam 3320 i\u015f\u00e7i ar\u0131 \u00f6rne\u011fi ile yap\u0131lan allozim \u00e7al\u0131\u015fmalar\u0131 sonunda Pgm genotip frekanslar\u0131n\u0131n yaz ve k\u0131\u015f populasyonlar\u0131nda mevsimsel varyasyon g\u00f6sterdi\u011fi ve Hardy-Weinberg dengesinden anlaml\u0131 \u00f6l\u00e7\u00fcde sapt\u0131\u011f\u0131 (P<0.001), kontrol olarak \u00e7al\u0131s\u0131lan Heksokinaz (Hk) lokusunda ise genotip frekanslar\u0131nda mevsime ba\u011fl\u0131 bir de\u011fi\u015fim olmad\u0131\u011f\u0131 belirlenmi\u015ftir. Farkl\u0131 Pgm genotiplerinin balar\u0131lar\u0131n\u0131n fizyolojik performans\u0131na etkisini belirlemek amac\u0131yla bu genotiplerin (Pgm-75\/75 ve Pgm-75\/100), PGM enzim aktivitesi ve glikojen miktarlar\u0131 belirlenmi\u015f ve k\u0131\u015f aylar\u0131nda frekans\u0131 y\u00fcksek olan heterozigot bireylerde PGM enzim aktivitesinin ve glikojen miktar\u0131n\u0131n, homozigot bireylere g\u00f6re \u00f6nemli \u00f6l\u00e7\u00fcde y\u00fcksek oldu\u011fu g\u00f6zlenmi\u015ftir (P<0.0001). Pgm aktiviteleri farkl\u0131 olan homozigot ve heterozigot bireylerle 50\u02daC de yap\u0131lan \u00f6l\u00e7\u00fcmler sonucu enzim \u0131s\u0131 dayan\u0131kl\u0131\u011f\u0131n\u0131n (termostabilite) aktivite ile ili\u015fkili olmad\u0131\u011f\u0131 ve farkl\u0131 genotipli bireyler aras\u0131nda enzim \u0131s\u0131 dayan\u0131kl\u0131l\u0131\u011f\u0131 bak\u0131m\u0131ndan \u00f6nemli bir fark olmad\u0131\u011f\u0131 belirlenmi\u015ftir (P=0.8879). Elde edilen bu veriler, farkl\u0131 Pgm genotiplerinin biyokimyasal farkl\u0131l\u0131klar\u0131n\u0131n bal ar\u0131lar\u0131n\u0131n glikojen d\u00fczeyindeki \u00f6nemli varyasyona yol a\u00e7an i\u015flevsel ili\u015fkileri oldu\u011funu ve uyumsal sonu\u00e7lar\u0131 olabilece\u011fini g\u00f6stermektedir.Y\u00fcksek enzim aktivitesi ve glikojen d\u00fczeyi k\u0131\u015f ar\u0131lar\u0131n\u0131n uzun \u00f6m\u00fcrl\u00fc olmalar\u0131n\u0131n temel mekanizmalar\u0131ndan biri olabilir. Yaz ar\u0131lar\u0131na k\u0131yasla uzun \u00f6m\u00fcrl\u00fc k\u0131\u015f ar\u0131lar\u0131 yavrusuz k\u0131\u015f kolonisinin ya\u015fayabilmesini sa\u011flamaktad\u0131r.<\/p>\n

Anahtar Kelimeler:<\/strong> Apis mellifera; Fosfoglukomutaz; allozim; enzim aktivitesi; glikojen miktar\u0131; mevsimsel de\u011fi\u015fim; \u0131s\u0131ya dayan\u0131kl\u0131l\u0131k<\/p>\n","protected":false},"excerpt":{"rendered":"

KENCE, Meral; BANERJEE, Sreeparma T\u00dcB\u0130TAK TBAG Proje 106T181, 2008: 1-54 Makale No:\u00a097989<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"footnotes":""},"categories":[33],"tags":[119,67,118],"class_list":["post-17199","post","type-post","status-publish","format-standard","","category-tubitak-destekli-projeler","tag-balarisi-ozellikleri","tag-meral-kence","tag-sreeparma-banerjee","yazarlar-filiz-yeni","yazarlar-meral-kence","yazarlar-sreeparma-banerjee","yazarlar-zerrin-gulduren","anahtarkelimeler-allozim","anahtarkelimeler-balarisi","anahtarkelimeler-enzim-aktivitesi","anahtarkelimeler-fosfoglukomutaz","anahtarkelimeler-glikojen-miktari"],"_links":{"self":[{"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=\/wp\/v2\/posts\/17199","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=17199"}],"version-history":[{"count":7,"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=\/wp\/v2\/posts\/17199\/revisions"}],"predecessor-version":[{"id":17655,"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=\/wp\/v2\/posts\/17199\/revisions\/17655"}],"wp:attachment":[{"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=17199"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=17199"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.beyazkovan.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=17199"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}